Human immunodeficiency virus, responsible for producing AIDS. Intensely itching raised areas of skin caused by an allergic reaction; hives. Loss of brain function due to a loss of blood supply. COX-2 inhibitors target pain and inflammation with fewer gastrointestinal side effects. 0000149592 00000 n

Hormone from adrenal medulla that stimulates adrenergic receptors, especially during stress. 0000134553 00000 n Microorganism capable of causing disease only when the resistance (immunocompetence) of the host is impaired. The ability of viruses to change the composition or structure of their surface proteins (viral coat) that are responsible for producing disease (pathogenicity). Drug that has the potential for abuse and thus is regulated by law. Secretion from the respiratory tract; usually called mucus. Drug used to produce mental relaxation and to reduce the desire for physical activity. Medications containing iron compounds, used to increase hemoglobin production. Absorption of drug through the mucous membranes lining the oral cavity. Suffix denoting killing, as of microorganisms. 0000004240 00000 n Drug that is effective against a wide variety of both gram-positive and gram-negative pathogenic bacteria. Tricyclic antidepressants, a class of antidepressant drugs. Anemia caused by defective functioning of the blood-forming organs (bone marrow). Seizure originating in one area of the brain that may spread to other areas. Refers to nerves of the ANS that originate in the brain and sacral portion of the spinal cord; they are active when the body is at rest or trying to restore body energy and function. Insufficient blood supply (and oxygen) to meet the needs of the tissue or organ; condition of insufficient tissue blood flow; reduction in blood supply and oxygen to localized area of the body or tissue insufficient blood flow to a tissue. Name that defines the chemical composition of a drug. Cyclooxygenases 1 and 2. Process through which red blood cells are produced. [Updated 2020 Jan 17]. Condition usually in middle-aged adults from hypersecretion of growth hormone. Inhibits the growth of fungi but does not kill off the fungi; chemical that inhibits growth or reproduction of fungi but does not kill fungi. Thyroid-stimulating hormone, secreted by the anterior pituitary. He is an associate professor at the University of Washington School of Medicine and the head of rheumatology at Seattle’s Harborview Medical Center. 0000018975 00000 n CNS depressant drug possessing the barbituric acid ring structure. 0000028069 00000 n

A blood clot that forms in a vein deep inside the body. Decimal fraction with a denominator of 100. Drug that stimulates the nicotinicneural (Nn) receptors to increase autonomic nervous system activity. Causing a muscle to contract intermittently, resulting in a state of spasms. One of the forms of cholesterol transported in the blood with lipoprotein; known as “good” cholesterol. Abnormal discharge of brain neurons that causes alteration of behavior and/or motor activity. The increased risk of heart attack or stroke from using NSAIDs applies to everyone, with or without heart disease or its risk factors. Movement disorder of the basal ganglia caused by a deficiency of dopamine. Occurring in the general circulation, resulting in distribution to most organs. Higher than normal level of glucose in the blood; fasting blood glucose higher than 126 mg/dl. A substance that causes constriction of the pupil or miosis. Flashcards. The relationship of one number to another expressed by whole numbers (1:5) or as a fraction (1/5). Nonsteroidal anti-inflammatory drugs (NSAIDs), commonly prescribed to treat many types of arthritis, work by inhibiting prostaglandins. Traditional NSAIDs, like Motrin (ibuprofen), aspirin, and Aleve (naproxen), while effective, can cause gastrointestinal problems including ulcers because they're non-selective, meaning they inhibit both COX-1 and COX-2. Drugs that only interact with one of the enzymes in the cyclooxygenase family. Chemical substance that produces a change in body function. Largest and uppermost part of the brain that is divided into right and left cerebral hemispheres. A drug or plant substance that produces psychotomimetic effects and sensory distortions. Abnormally high fat (lipid) levels in the plasma. Lack of responsiveness of cancer cells to chemotherapy. Specialized cardiac tissue that transmits electrical impulses and regulates the activity of the heart. Causing destruction of bacterial protein function; also adulteration of alcohol, rendering it unfit for drinking. Patented proprietary name of drug sold by a specific drug manufacturer; also referred to as the brand name. Difficult or painful menstruation; condition that is associated with painful and difficult menstruation. Substance that relaxes the muscles (sphincters) controlling blood vessels, leading to increased blood flow. The ability to prevent or stop atherosclerosis, the deposition of lipid-containing plaques on the innermost layers of the arteries. If you simply need pain relief, Tylenol (acetaminophen) may be considered instead. Effective dose 50, or dose that will produce an effect that is half of the maximal response. Drug microsomal metabolizing enzymes (DMMS) that decrease with age and slow the rate of drug oxidation and metabolism. After ingestion is converted to the hormone testosterone. An abnormal decrease in the number of circulating platelets. Network of nerve fibers that travel throughout the central nervous system that regulates the level of wakefulness. Sibbald B. Rofecoxib (Vioxx) voluntarily withdrawn from market. 0000003379 00000 n Spread of cancer cells throughout the body, from primary to secondary sites. Drug effect other than the therapeutic effect that is usually undesirable but not harmful. Steroid produced within the adrenal cortex that directly influences sodium and potassium metabolism. Acute condition in which there is a reduction in the number of white blood cells (WBCs), specifically polymorphonuclear cells (granulocytes); condition in which the number of white blood cells, in particular the granulocytes, is less than normal. 0000149363 00000 n Phenomenon occurring long after the use of LSD in which the hallucinogenic effects are relived in some type of memory flash. Muscle spasms, facial grimacing, and other involuntary movements and postures. Route of drug administration; drug is injected directly into a vein.

0000020353 00000 n Refers to the action of an adrenergic drug or an action that increases sympathetic activity. Condition, also called delayed gastric emptying, in which the stomach muscles do not function properly. Convulsive muscle contraction in which rigidity and relaxation alternate in rapid succession. Nonsteroidal Anti-inflammatory Drugs (NSAIDs), Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain, Nonsteroidal Anti-Inflammatory Drugs (NSAID) Toxicity, New insights into the use of currently available non-steroidal anti-inflammatory drugs, Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships, (Vioxx) voluntarily withdrawn from market, COX 2 inhibitor rejected in North America but retained in Europe, FDA Drug Safety Communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokes, Are All Oral COX-2 Selective Inhibitors the Same? Man-made form of ADH. 0000043322 00000 n Space around the brain and spinal cord that contains the cerebrospinal fluid. 8�vggy1W�p=Ѯ��21G���� H[�mn�.�.�������Qp1��kM��g�—#��=�2\I�Hq�Ź��L��Q Amphetamine or related drug that increases mental and physical activity. An arrhythmia caused by administration of an antiarrhythmic drug. 0000024104 00000 n Carries the appropriate motor response from the brain and spinal cord to the peripheral organs.

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